Proceedings: Assay of steroid hormone receptor in cancers, methodology and perspectives
نویسندگان
چکیده
منابع مشابه
Role of steroid receptor and coregulator mutations in hormone-dependent cancers.
Steroid hormones mediate critical lineage-specific developmental and physiologic responses. They function by binding their cognate receptors, which are transcription factors that drive specific gene expression programs. The requirement of most prostate cancers for androgen and most breast cancers for estrogen has led to the development of endocrine therapies that block the action of these hormo...
متن کاملepidemiological study of oral and pharyngeal cancers in kermanshah province from march 1993 to march 2006
چکیده ندارد.
15 صفحه اولThe Endocannabinoid System and Sex Steroid Hormone-Dependent Cancers
The "endocannabinoid system (ECS)" comprises the endocannabinoids, the enzymes that regulate their synthesis and degradation, the prototypical cannabinoid receptors (CB1 and CB2), some noncannabinoid receptors, and an, as yet, uncharacterised transport system. Recent evidence suggests that both cannabinoid receptors are present in sex steroid hormone-dependent cancer tissues and potentially pla...
متن کاملSteroid hormone receptor homologs in development.
The steroid/thyroid receptor superfamily are ligand-dependent transcription factors which consist of distinct functional domains required for transcriptional control of a network of genes. Members of this superfamily are beginning to be studied for their contribution to embryogenesis. Two human receptors for the vertebrate morphogen retinoic acid have been isolated and further characterized on ...
متن کاملHormone receptor expression in male breast cancers.
SummaryMale breast cancers are rare but have been found in higher proportions in Black Africans. Prognostic factors for breast cancers include tumour size, grade and stage, and hormone receptor status. The hormone receptor status is an invaluable guide in the use of adjuvant endocrine therapy, but none of the reports available in the literature from Africa showed any receptor work.This study wa...
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ژورنال
عنوان ژورنال: British Journal of Cancer
سال: 1974
ISSN: 0007-0920,1532-1827
DOI: 10.1038/bjc.1974.177